| Research: I am trying to use
population genetics tools to model / analyze the long term phage evolution
and to explain the rather puzzling "constant adaptation rate" of phage
evolution in a constant environment (Genetics 170: 19-31). In the
retrospective, some key parameters (mutation rate, recombination rate,
etc.) can be estimated using serial sequence data. While in the
prospective, I am motivated, by the data, to study the advantage of
recombination in the context of "adaptive walk" (Nature Genetics 37,
441-444) and density dependent selection.
Link to
my web page |