Center for Research
on Processes in Evolution (CRePE)
The Center for Research on Processes in Evolution (CRePE) at
the University of Idaho (UI) brings
together scientists that have expertise
in evolutionary biology, structural
biology, molecular biology, ecology,
computational biology, genetic
programming, and statistics to
investigate the relative importance of
various mutagenic processes on the tempo
and trajectory of adaptive evolution, to
detect and understand the functional
significance of patterns that emerge
during the course of evolution, and to
develop computational approaches that
improve our ability to understand the
evolutionary history of functional
domains in proteins, structural genes,
and entire genomes. The fundamental
knowledge gained from these studies will
be of broad significance to biomedical
science and provide insights to the
mechanisms and significance of genetic
variation in populations and how
adaptive evolution shapes the phenotypic
characteristics of all living organisms.
The specific aims of the Center are:
(1) Establish a
Center of
Biomedical Research Excellence (COBRE) at the
University of Idaho that facilitates
theoretical and empirical research by a
multidisciplinary team of scientists in
order to increase understanding of
evolutionary processes.
(2) Expand and
enhance the ability of existing
Bioinformatics and Molecular Biology
Core Facilities to support the research
and education activities of
participating faculty and other
researchers and students at the
University of Idaho.
(3) Establish a
Core Facility in Structural Biology at
the University of Idaho participating
faculty and other researchers and
students at the University of Idaho to
study protein structure.
(4) Establish
an administrative structure for the
Center that fosters interdisciplinary
collaboration, mentors faculty, and
monitors research projects to identify
ideas and findings that could form the
basis of a new competitive research
proposal.
The participating researchers
will increase their competitiveness for
extramural funding by developing a more
holistic understanding of research
opportunities in biological and
computational sciences, as well as by
establishing productive collaborations
with investigators from other fields
both at UI and elsewhere. Funding will
also be used to enhance the capabilities
of Core Facilities in Bioinformatics and
Molecular Biology and to establish a
third in Structural Biology. These
resources will provide CRePE
investigators access to advanced
analytical instrumentation,
computational hardware and software, as
well as the expertise and technical
support. In addition, these improvements
to the UI research infrastructure will
be used for the instruction of
undergraduate and graduate students at
UI and thereby provide broad benefit.
Researchers
|
Larry
J. Forney |
University of
Idaho,
Biological Sciences |
Program
Director |
|
Holly
A. Wichman |
University of
Idaho,
Biological Sciences |
Research
Project Leader |
|
Eva M. Top |
University of
Idaho,
Biological Sciences |
Research
Project Leader |
|
Gary W.
Daughdrill |
University of
Idaho,
MMBB |
Research
Project Leader |
|
James
A. Foster |
University of
Idaho,
Computer Science |
Research
Project Leader |
|
Robert B.
Heckendorn |
University of Idaho,
Computer
Science |
Faculty
Researcher |
|
Paul Joyce |
University of
Idaho,
Mathematics |
Faculty
Researcher |
|
Stephen,
M. Krone |
University of
Idaho,
Mathematics |
Faculty
Researcher |
|
Terence Soule |
University of
Idaho,
Computer Science |
Faculty
Researcher |
|
John
M. (Jack) Sullivan |
University of
Idaho,
Biological Sciences |
Faculty
Researcher |
|
James Bull |
University of
Texas, Biological Sciences |
Collaborator,
Project 1 |
|
Christopher M.
Thomas |
University of
Birmingham, UK, Biosciences |
Collaborator,
Project 2 |
Projects
Core Facilities
Links
|
