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Glossary
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electromagnetic radiation
Range of energy-containing wavelengths, including radio waves, infrared
radiation, visible light, UV light, and X-rays. |
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Electron transfer chain
The electron
transfer chain, also called the electron transport chain, is a sequence of
complexes found in the mitochondrial membrane that accept electrons from
electron donors such as NADH or succinate, shuttle these electrons across the
mitochondrial membrane creating an electrical and chemical gradient, and, through
the proton driven chemistry of the ATP synthase,
generate adenosine triphosphate.
There are five complexes normally associated with the electron
transfer chain.
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Complex I - NADH dehydrogenase, also called NADH Coenzyme Q
reductase.
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Complex II - Succinate - Coenzyme Q reductase.
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Complex III - Coenzyme Q - cytochrome c reductase.
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Complex IV - Cytochrome c oxidase.
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Complex V - ATP Synthase, also known as the F0F1 particle.
Complexes I, III, and IV are proton pumps. Complex II is part of the
Krebs cycle and does not pump protons, and Complex V uses the electrochemical
potential generated to create ATP. Complex IV is the terminus of the electron
transfer chain, consuming oxygen and making water.
Cytochrome c is also an essential part of the electron transfer
chain. It is a soluble protein loosely associated with the inner mitochondrial
membrane, and transfers electrons between Complexes III and IV. |
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endergonic reaction
One for which energy must be supplied. |
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endocytosis
Endocytosis refers to a biological process whereby cells
absorb material outside their cell membranes. Endocytosis is the opposite of
exocytosis, and always involves the formation of a vesicle from part of the
cell membrane. Endocytosis can be of three forms:
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Pinocytosis (literally, cell drinking) is the invagination of
the cell membrane to form a pocket filled with extracellular fluid. The
pocket then pinches off to form a vesicle, and the vesicle ruptures to
release its contents into the cytosol.
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Receptor-mediated endocytosis is similar to pinocytosis, except it is
prompted by the binding of a large extracellular molecule - such as a
protein - to a receptor on the cell membrane. The invagination that results
engulfs the protein, which is then released into the cytosol.
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Phagocytosis is the process by which cells ingest large objects, such as
prey cells or large chunks of dead organic matter. These are sealed off into
large vacuoles. Lysosomes then merge with the vacuole, turning it into a
digestive chamber. The products of the digestion are then released into the
cytosol. Macrophages are cells of the immune system that specialize in the
destruction of bacteria by phagocytosis.
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enzyme
Proteins (usually) that catalyze specific biochemical reactions.
An enzyme is a special
protein molecule whose function is to facilitate or otherwise accelerate most
chemical reactions in cells. Many chemical reactions occur within biological
cells, but without catalysts most of them happen too slowly in the test tube to
be biologically relevant. Enzymes can also serve to couple two or more
reactions together, so that a thermodynamically favorable reaction can be used
to "drive" a thermodynamically unfavorable one. One of the most common examples
is enzymes which use the dephosphorylation of ATP to drive some otherwise
unrelated chemical reaction. |
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epistasis
A genetic interaction whereby the expression of one gene affects the
phenotypic expression of another gene. |
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equilibrium
A state at which the forward and reverse reactions are proceeding at
equal rates. |
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ester linkages
A condensation (water-releasing) reaction in which the carboxyl group of a fatty
acid reacts with the hydroxyl group of an alcohol. Lipids are formed in this
way. |
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eukaryotic
Organisms with membrane-bound nuclei and organelles; comprise the protist,
plant, fungi, and animal kingdoms. |
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evolution
A change in the genetic structure of a population; gradual changes that
occur in the characteristics of a species. |
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exergonic reaction
A reaction in which free energy is released. |
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exocytosis
Exocytosis is the
process of a biological cell releasing substances into the
extracellular fluid (its environment). Exocytosis is the opposite of
endocytosis. |
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exon
In eukaryotic DNA, a portion of a gene that codes for a polypeptide. |
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